Vitamin C
Vitamin C
| Classification of vitamins 1.Water soluble Vitamins: a.B-Complex B1 (Thiamin) B2 (Riboflavin) B3 (Nicotinic acid) B5 (Pantothenic acid) B6 (Pyridoxine) B12 (Cyanocobolamin) Folic acid (M) Choline Inositol Para Amino Benzoic acid Biotin (h) b.Vitamin C (ascorbic acid) 2.Fat soluble vitamins *Vitamin D *Vitamin A *Vitamin E *Vitamin K |
Properties
Vitamin C was known with its deficiency disease called scurvy, the incidence of scurvy
was reduced by the introduction of the potato (a source of vitamin C) to the Europe in the
seventeenth century
Ascorbic (a-SKOR-bik) acid, also known as vitamin C, It is water-soluble vitamin, is
necessary for wound healing. It is needed for many functions in the body, including helping
the body use carbohydrates, fats, and protein. Vitamin C also strengthens blood vessel
walls.
Most animals synthesis their own vitamin C, but humans must relay upon dietary sources.
Vitamin C plays a primary role in the formation of collagen, which is important for the
growth and repair of body tissue cells, gum, blood vessels, bone and teeth.
Chemistry:
It is reversibly oxidized in the body into dehydroascorbic acid .The later compound
posses full vitamin C activity
Ascorbic Acid
Dehydroascorbic Acid
Physiological functions:
-Ascorbic acid functions as a cofactor in a number of hydroxylation and amidation
reactions.
-Ascorbic acid required for collagen synthesis, conversion of folic acid to folenic acid,
microsomal drug metabolism, and the hydroxylation of dopamine to form norepinephrine
-Ascorbic acid promotes the activity of an amiding enzyme thought to be involve in the
processing of certain peptide hormones such as: oxytocin, antiduiretic hormone “ADH”,
and cholecytokinin
- Ascorbic acid also promotes intestinal absorption of iron
By reducing the non-heme ferric iron to the ferrous state (conversion of folic acid to folenic
acid) in the stomach.
Absorption:
Ascorbic acid readily absorbed from the intestine, and absorption of the dietary
ascorbate is nearly complete.
Ascorbic acid presents in the plasma and is ubiquitously distributed in the cell of the body
The white blood cells of the healthy adult have concentration of about 27 µg of Ascorbic
acid per 108 cells
Adequate ingestion is associated with concentrations over
0.5 mg/dl (28 µm), whereas concentration of 0.15 mg/dl
(8.5 µm) are seen in individuals with frank scurvy.
Vitamin C was known with its deficiency disease called scurvy, the incidence of scurvy
was reduced by the introduction of the potato (a source of vitamin C) to the Europe in the
seventeenth century
Ascorbic (a-SKOR-bik) acid, also known as vitamin C, It is water-soluble vitamin, is
necessary for wound healing. It is needed for many functions in the body, including helping
the body use carbohydrates, fats, and protein. Vitamin C also strengthens blood vessel
walls.
Most animals synthesis their own vitamin C, but humans must relay upon dietary sources.
Vitamin C plays a primary role in the formation of collagen, which is important for the
growth and repair of body tissue cells, gum, blood vessels, bone and teeth.
Chemistry:
It is reversibly oxidized in the body into dehydroascorbic acid .The later compound
posses full vitamin C activity
Ascorbic Acid
Dehydroascorbic Acid
Physiological functions:
-Ascorbic acid functions as a cofactor in a number of hydroxylation and amidation
reactions.
-Ascorbic acid required for collagen synthesis, conversion of folic acid to folenic acid,
microsomal drug metabolism, and the hydroxylation of dopamine to form norepinephrine
-Ascorbic acid promotes the activity of an amiding enzyme thought to be involve in the
processing of certain peptide hormones such as: oxytocin, antiduiretic hormone “ADH”,
and cholecytokinin
- Ascorbic acid also promotes intestinal absorption of iron
By reducing the non-heme ferric iron to the ferrous state (conversion of folic acid to folenic
acid) in the stomach.
Absorption:
Ascorbic acid readily absorbed from the intestine, and absorption of the dietary
ascorbate is nearly complete.
Ascorbic acid presents in the plasma and is ubiquitously distributed in the cell of the body
The white blood cells of the healthy adult have concentration of about 27 µg of Ascorbic
acid per 108 cells
Adequate ingestion is associated with concentrations over
0.5 mg/dl (28 µm), whereas concentration of 0.15 mg/dl
(8.5 µm) are seen in individuals with frank scurvy.
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