Vitamin E
Vitamin E
VITAMIN E

Properties:

Fat soluble and stored in liver, fatty tissues, testes, uterus, blood, adrenal and pituitary gland.
Composed of compounds called tocopherols. Of the eight tocopherols –alpha- beta- gamma, delta,
epsilon, zeta, eta, and theta. Alpha tocopherol is the most effective.

The vitamin was isolated from wheat germ oil 8 naturally occuring tocopherols with vitamin E activity are
known now. Alpha-tocopherol is considered to be the most important tocopherol since it comprises
about 90% of the tocopherols in the animal tissues and display the greatest biological activity in most
bioassay systems.


One of the important chemical features of tochoferols is that they are antioxidants, and this apparently
is the basis for most if not all of the vitamin E.

Vitamin E prevents a chemical reaction called oxidation, which can sometimes result in harmful effects
in your body. It is also important for the proper function of nerves and muscles Vitamin E is an important
anti-oxidant. It acts as a free radical scavenger to prevent the byproducts of chemical-cell interaction to
cause cell damage.

Free radicals

Free radicals are likely responsible for all or most of the degenerative diseases e.g. arthritis, heart
disease, cancer, senility etc.

The absorption or scavenging of free radicals would protect our cells from this type of injury. Other free
radical scavengers include zinc, vitamin C, and selenium. Studies have reported vitamin E to protect
against some of the toxicity’s of ionizing radiation.

       
Vitamin E may help to decrease the toxicity of certain chemotherapy drugs. A driamycin is an important
anti-cancer drug with potential major toxicity to the heart. The use of 1000 to 2,000 units of vitamin E per
day may help to decrease this toxicity. Vitamin E may decrease some of the harmful effects of solar
radiation on the skin. As cited above it works well in conjunction with beta carotene.

Vitamin E appears to have stabilizing effect on the vascular system and is useful in decreasing
menopausal and premenstrual symptoms. It is useful in decreasing leg cramps occurring especially at
night. Vitamin E can be used in lotions or creams to protect the skin or to treat for burns. It is also
helpful to treat burns secondary to radiation therapy. Also used dermatitis resulting from poor blood
circulation i.e. stasis dermatitis. It is commonly prescribed for topical use in pregnant women to prevent
stretch marks on the abdomen. More recently it has been used to prevent or treat mucositis resulting
from chemotherapy

Importance:
Major anti-oxidant nutrient; retards cellular aging due to oxidation; supplies oxygen to the blood which is
then carried to the heart and other organs; thus alleviating fatigue; aids in bringing nourishment to
cells; strengthens the capillary walls & prevents the red blood cells from destructive poisons; prevents
& dissolves blood clots; has also been used by doctors in helping prevent sterility, muscular dystrophy,
calcium deposits in blood walls and heart conditions.


Deficiency

May lead to a rupture of red blood cells, loss of reproductive powers, lack of sexual vitality, abnormal fat
deposits in muscles, degenerative changes in the changes in the heart and other muscles; dry skin.
SPECIAL NOTE: There are several types of Vitamin E available.
D-Alpha Tocopherol (100% Natural) is 4 times more potent in biological activity than d1-Alpha
Tocopherol (Synthetic) Vitamin E. For example; 100 I.U. of d-Alpha (100% Natural) Vitamin E is equal to
400 I.U. d1-Alpha Tocopherol (Synthetic) Vitamin E in biological activity. Natural Vitamin E is derived
from soybeans and synthetic Vitamin E is a petroleum by-product.

Some conditions may increase your need for vitamin E. These include:

Intestine disease, Liver disease, Pancreas disease and Surgical removal of stomach

Infants who are receiving a formula that is not fortified with vitamin E may be likely to have a vitamin E
deficiency. Also, diets high in polyunsaturated fatty acids may increase your need for vitamin E.

Claims that vitamin E is effective for treatment of cancer and for prevention or treatment of acne, aging,
loss of hair, bee stings  , liver spots on the hands, diaper rash, frostbite, stomach ulcer, heart attacks,
labor pains, certain blood diseases, miscarriage, muscular dystrophy, poor posture, sexual impotence,
sterility, infertility, menopause, sunburn, and lung damage from air pollution have not been proven.
Although vitamin E is being used to prevent certain types of cancer, there is not enough information to
show that this is effective.

Lack of vitamin E is extremely rare, except in people who have a disease in which it is not absorbed into
the body.

Human requirement
The daily amount of vitamin E needed is defined in several different ways.

Vitamin E is available in various forms, including d- or dl-alpha tocopheryl acetate, d- or dl-alpha
tocopherol, and d- or dl-alpha tocopheryl acid succinate.

In the past, the RDA for vitamin E have been expressed in Units. This term has been replaced by alpha
tocopherol equivalents (alpha-TE) or milligrams (mg) of d-alpha tocopherol. One
Unit is equivalent to 1 mg of dl-alpha tocopherol acetate or 0.6 mg d-alpha tocopherol. Most products
available in stores continue to be labeled in Units.

Normal daily recommended intakes in milligrams (mg) of alpha tocopherol equivalents (mg alpha-TE)
and Units for vitamin E are generally defined as follows:

mg
alpha-TE Units mg
alpha-TE Units

Proper Use of This Dietary Supplement
Dosing—The amount of vitamin E needed to meet normal daily recommended intakes will be different
for different individuals.
To prevent deficiency for individuals (other than infants), the amount taken by mouth is based on
normal daily recommended intakes:


Adult and teenage males—10 milligrams (mg) of alpha tocopherol equivalents (mg alpha-TE) or 16.7
Units per day.

Adult and teenage females—8 mg alpha-TE or 13 Units per day.

Pregnant females—10 mg alpha-TE or 16.7 Units per day.

Breast-feeding females—11 to 12 mg alpha-TE or 18 to 20 Units per day.


Bleeding problems—Vitamin E, when taken in doses greater than 800 Units a day for long periods of
time, may make this condition worse


Food source
Vitamin E is found in various foods including vegetable oils (corn, cottonseed, soybean, safflower),
wheat germ, whole-grain cereals, and green leafy vegetables. Cooking and storage may destroy some
of the vitamin E in foods.

Small amounts of fat are needed so that vitamin E can be absorbed into the body.

Toxicity
Essentially non toxic

Side Effects of This Dietary Supplement
Along with its needed effects, a dietary supplement may cause some unwanted effects. When used for
short periods of time at recommended doses, vitamin E usually does not cause any side effects.
However, check with your health care professional as soon as possible if any of the following side
effects occur:

With doses greater than 400 Units a day and long-term use

Blurred vision; diarrhea; dizziness; headache; nausea or stomach cramps; unusual tiredness or
weakness
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